SPR-BI 2000 Series
Key Features •Innovative multi-module design Provides users with maximum flexibility to choose amongst various analysis modules for diverse applications
• Compatible with electrochemistry and chemical vapor applications Allows for electrochemical SPR studies, chemical vapor detection, gas chemical sensor research, and fundamental solid-gas interface studies (gas module exclusive to BI-2000G model)
• Two-channel SPR detection module For background and reference subtraction in aqueous buffer solution; covers SPR angle range for measuring SPR shift
• Single and dual channel flow modes Allows for more experimental options and enhanced data quality
• Wide dynamic range and high sensitivity High sensitivity (<10-4 degrees) for both large and small molecules (<100 Daltons) enables users to measure binding constants down to a few pM-1
• Broad response time For slow (hours) and fast (< ms) kinetic processes
Analysis Modules Included: Flow Injection Module for two-channel flow injection SPR research
Gas SPR Module for gas phase and chemical vapor SPR research *included in BI-2000G model only
Optional Accessories: EC-DualFlow™ Module for advanced two-channel electrochemical (EC) flow SPR research
EC-SPR Module for electrochemical (EC) SPR research BI Sensor Chips with high uniformity for reproducible SPR research
BI-SPR System Specifications
SPR Base Station Two-channel SPR Detection Unit
With differential detection electronics for high sensitivity and fast detection
Broad detection range for measuring SPR binding in liquid and gas mediums Accurate background and reference subtraction Broad response window for slow and fast kinetics analysis Viewable SPR profile for SPR quality and chip evaluation Thermal isolation technology to minimize thermal drift
Versatile in Application
One instrument for numerous applications
Interchangeable analysis modules for different research needs Accessible detection area and auxiliary data IO ports to facilitate project integration Small footprint to save valuable lab space USB connectivity for convenient transportability
Fluid Handling
Flow Injection System For two-channel precision sample delivery
Continuous flow stream for uninterrupted binding studies Single and Serial flow modes Zero-dead volume injection valves for negligible sample carry over HPLC-type components for convenient and low cost maintenance
Precision Syringe Pump
Two-channel programmable syringe pump for uniform continuous flow
Wide flow range from tens of nanoliters to milliliters a minute(depending upon syringe size) Accurate, precise, and steady flow resulting in stable baselines and high quality data Quiet and easy operation
Control System
Control/Analysis Software Powerful and easy-to-use software package
Collect SPR data in real-time Programmable injection timers for accurate sample delivery Easily manage and/or overlay multiple data files Smart Wizards to guide user through instrument operation Powerful analysis tools to evaluate binding interactions, i.e. affinity, kinetics, concentration, and more Tools to compensate for bulk refractive index shift, non-specific adsorption, mass limited transport, noise, and more Select amongst various SPR operational modes for optimized performance, i.e. flow injection, gas, and EC
Computer
PC with pre-installed BI software package Windows 7 operating system Ethernet connectivity (direct on-line customer support available) USB connectivity to BI-SPR instruments for transportability
Application
Life Science
Our Flow injection technique and analysis modules can help you with drug discovery and development, protein-protein/ protein-DNA/ protein-drug interaction studies, gene assays, immunosensing, and more.
Electrochemistry
Our Electrochemical SPR technique and analysis modules can help you with a variety of electro-analytical applications such as anodic stripping analyses, electropolymerization, electrodeposition, redox-related conformational change, and more.
Chemical Vapor Sensing
Our Gas Phase SPR technique and analysis modules can help you study fundamental solid-gas interface interactions, detect toxic molecules in the environment, perform various chemical analyses for medical research, and more.
Environment, Food & Beyond
Our BI-SPR techniques can help you with broader applications such as food safety, quality control, environmental monitoring, or the development of new high-performance and coupled SPR techniques.
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